Keloids and Scars

Keloid scar removal - Courtesy of S. Otuoke, MD

The therapy of choice for recent red scars with strong vascularization is the 532 nm green fractional laser (see LASEmaR® 500).

As for the laser treatment of keloids and hypertrophic scars, the inhibitory effect of high-energy near infrared diode laser therapy (see LASEmaR® 800) on vascular and endothelial growth factors of keloid lesions and hypertrophic scars is documented by the Arnld-Schultz law.

The Arnld-Schultz Law or law of stimuli

Hormesis, from the Greek verb ormao, which means to stimulate, is a dose / response relationship characterized by a biphasic effect: many organisms exposed to a wide range of stimuli show opposite responses depending on the dose; hormesis is considered an adaptive function (Amendola, Cerioli, Migliore, 2006, 2008).

The hormetic responses are characterized by a modest stimulation of the affected function at low doses and by its inhibition at high doses.

We can therefore compare and enegetic principle to the phenomenon of water:

a stimulus of a minimal amount (e.g.: water drops) results in plant growth;
an elevated stimulus (e.g.: flood) drowns and inhibits plant growth;
an eradicating or destructive stimulus (e.g.: vigorous jet of water) destroys the plant.

Eufoton®'s experience confirms the expectations of synergistic use of hormetic high power diode laser therapy in the N.IR region even in plastic surgery.

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The therapeutic use of N.IR. diode combined with the Multi-Therapy handpiece resolved 70% of recent keloid cases after six to seven sessions, with excellent results in terms of reduction in the symptoms, the absence of itching and healing of the lesions. The psychological outcome was equally satisfactory in these patients.

The remaining 30% of the patients with keloids overall saw a significant improvement both physically and psychologically: the recurrent keloids were very small in size, caused no itching and aesthetically did not have a disfiguring appearance.

The surgical advantage is the vasoconstriction of the tissues undergoing the therapy.

With regard to small scars resulting from surgery, minor accidents, and so on, non-ablative fractional laser therapy (1470 nm or 1940 nm - see LASEmaR® 1500, LASEmaR® 2000 and Spectrum® is a well-established practice in dermatological plastic surgery.

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